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M-Ibuprofene - Tablet 400mg



Leaflet;indication

FORM AND PRESENTATION
Pink, round and convex sugar-coated tablet.
10 tablets by blister.

COMPOSITION PER TABLET
Ibuprofene (INN) BP 400mg

PROPERTIES
Non-steroidal anti-inflammatory drug (NSAID) with an antialgic and antipyretic effect.
Ibuprofene inhibits production of prostaglandines.
Also active against platelet function.

INDICATIONS
Symptomatic treatment during long chronic inflammatory rheumatism.
Short symptomatic treatment of acute attacks of abarticular rheumatism.
Tendinitis, periarthrite, lumbago, osteoarthrisis, bout of gout.
Essential dysmenorrhoea.
Symptomatic treatment of pain and fever.

DOSAGE
Swallow the tablets with a large glass of water, preferably during meals.
Adults : for an attack treatment : 2 tablets, 3 times a day.
For a keep treatment : 1 tablet, 3 to 4 times a day.
Others : 1200 to 1600mg/d, i.e. 1 tablet, 3 to 4 times a day.

CONTRAINDICATIONS
Allergy to Ibuprofene and to any NSAID.
Evolutive gastro-duodenal ulcer or past history of ulcer.
Renal or hepatic deficiency.
Children under 15 years.

INTERACTIONS
Risk of hyperkaliemie during the association with :
Potassium salts, hyperkaliemiant diuretics, converting enzyme inhibitor, trimethoprime.
It is strongly advised against associating the Ibuprofene with : other NSAID, oral anticoagulants and CEI.

PRECAUTIONS AND WARNINGS
Late pregnancy and lactation.
Association with diuretics.

ADVERSE EFFECTS
Digestive accidents : esophagites, gastritis.
Hematological accidents : such as rare leucopenies.
Awareness accidents : pruritus, urticaria, Quincke’s aedema, asthma.